document.write('<a href="http://www.cshblogs.org/cshprotocols/2010/02/01/high-throughput-analysis-of-gene-regulation/" title="High-throughput Analysis of Gene Regulation"  target=_blank style="font-size:120%;font-weight:bold;color:#036;">High-throughput Analysis of Gene Regulation</a><br><a href="http://www.cshblogs.org/cshprotocols/2010/02/01/high-throughput-analysis-of-gene-regulation/"  target=_blank style="line-height:20px;font-size:90%;color:#666666;text-decoration:none;">Mon, 01 Feb 2010 16:53:06 +0000</a><br>Mapping DNase I hypersensitive sites has long been the standard method for identifying genetic regulatory elements such as promoters, enhancers, silencers, insulators, and locus control regions. Sequences that are nucleosome-depleted, presumably to provide access for transcription factors, are selectively digested by DNase I.  Traditional low-throughput methods use Southern blots to then identify these hypersensitive [...]');